Resources
Precision Medicine to Improve Treatment of Post-Concussion Syndrome
Post-concussion syndrome is diagnosed in approximately 1 in 3 people who sustain a concussion. Symptoms include mental, emotional, and physical problems that can last months. We are using electronic health record data on thousands of people to understand genetic, lifestyle, and environmental factors that increase a person’s risk for developing post-concussion syndrome. These discoveries could lead to better treatments for people affected by post-concussion syndrome.
Video abstract [Youtube video] of research published in the paper: “Diagnostic Algorithms to Study Post-Concussion Syndrome Using Electronic Health Records: Validating a Method to Capture an Important Patient Population”
Link to interactive plots and complete results, as presented in the paper: “A phenome-wide association study identifying risk factors for pediatric post-concussion syndrome”
LabWAS in Electronic Health Records
Link to interactive plots and complete results, as presented in the paper: “Lab-wide association scan of polygenic scores identifies biomarkers of complex disease”